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Phenotypes

Credit: Waglione/Images compiled from video/CC by-SA 3.0
App helps patients with MS learn their clinical phenotype

App helps patients with MS learn their clinical phenotype

About one in five patients with multiple sclerosis don’t know their clinical phenotype – information that may help inform long-term treatment options for their disease, according to research presented at the 2020 virtual annual meeting of the Consortium of Multiple Sclerosis Centers.

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Projection neuron vulnerability suggests a therapeutic path

Projection neuron vulnerability suggests a therapeutic path

Region- and lineage-specific transcriptomic changes appear to be responsible for the characteristic pathobiology of multiple sclerosis (MS).
A study that used single-nucleus RNA sequencing to assess changes in cell lineages in MS lesions has shed light on the selective cortical neuron damage and glial activation that contribute to the progression of MS lesions.

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